Tuesday, December 11, 2007

Treatment Options for the Eradication of Intestinal Protozoa. Part 2


Various antiparasitic agents have been shown to be effective in the
intervention of the symptoms of giardiasis and in the eradication of
the sponger. A recent meta-analysis involving 34 trials performed by
the Cochrane collaborationism indicates that the preferred discussion
regimen is an ultra-short alimentation (i.e. a bingle dose regimen
taken on 1 day) of a nitroimidazole word.

Albendazole derivatives act by causing DNA hurt, with loss of the
helical social system, impaired template affair and fiber change of
integrity.
Metronidazole is commonly given as 2 g base hit dose on 3 successive
days (efficacy 60–100%, median 92%), or tinidazole is given as a 2 g I
dose (efficacy 80–100%, median 92%).
Other nitroimidazole derivatives, including ornidazole and secnidazole,
are also effective as single-dose therapies.

Nitrofuran compounds can also be used to sustenance G. intestinalis
contagion.
Furazolidone damages intracellular components, including DNA.
It has a lower efficacy than the nitroimidazole derivatives, but is
popular for the management of giardiasis in children because it has
relatively few adverse effects and is available as a reprieve.
Efficacy rates of 80–96% are reported, but the drug needs to be
administered for 7–10 days, which can ending in problems with
complaisance.



This is a part of article Treatment Options for the Eradication of Intestinal Protozoa. Part 2 Taken from "Albendazole (Generic Albenza) Information" Information Blog

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