Antiparasitic Therapy Reduces Seizures in Neurocysticercosis. Part 1

Jan. 14, 2007 — Antiparasitic therapy is appropriate and reduces the
bit of seizures associated with neurocysticercosis, according to the
results of a double-blind, randomized proceeding published in the Jan.
15 payoff of the New England Periodical of Drug.
The editorialist agrees.

“Neurocysticercosis
is the main drive of adult-onset seizures in the developing creation,”
write Héctor H.
Garcia, MD, and colleagues from the Cysticercosis Working Chemical
group in Lima, Peru. “Whether therapy with antiparasitic agents results
in improved attack command has been questioned because of the lack of
adequate, controlled studies.”

In
this learning, 120 patients with life cysticerci in the brainiac and
seizures treated with antiepileptic drugs received either 800 mg of
albendazole and 6 mg of dexamethasone daily or two placebos for 10
days.
Follow-up continued for 30 months or until patients were seizure-free
for six months after tapering doses of their antiepileptic drugs.

In
the albendazole set, the positive identification of seizures decreased
by 46% (95% self-assurance distance [CI], –74% to 83%) during months 2
to 30 after discussion.
Although the reduction in unit company of seizures and in public
presentation of derivative seizures was not statistically significant,
the definite quantity of seizures with colligation decreased
significantly by 67% (95% CI, 20% to 86%).

Most
of the variation in the definite quantity of differential seizures
resulted from a few patients with many seizures during follow-up.
The proportions of patients with first derivative seizures during
follow-up were similar in both groups (19 of 57 in the albendazole
abstract entity and 16 of 59 in the medicinal drug group), but more
patients in the medicine grouping had seizures with generality (22 of
59 vs. 13 of 57; risk magnitude relation, 1.63; 95% CI, 0.91 to 2.92).

This is a part of article Antiparasitic Therapy Reduces Seizures in Neurocysticercosis. Part 1 Taken from "Albendazole (Generic Albenza) Information" Information Blog